Article
A polygenic risk score for breast cancer risk in a Taiwanese population.
Breast cancer research and treatment - 1 May 2017
Hsieh Yi-Chen, Tu Shih-Hsin, Su Chien-Tien, Cho Er-Chieh, Wu Chih-Hsiung, Hsieh Mao-Chih, Lin Shiyng-Yu, Liu Yun-Ru, Hung Chin-Sheng, Chiou Hung-Yi
Abstract excerpt
BACKGROUND: Multiple common variants identified by genome-wide association studies showed limited evidence of the risk of breast cancer in Taiwan. In this study, we analyzed the breast cancer risk in relation to 13 individual single-nucleotide polymorphisms (SNPs) identified by a GWAS in an Asian population. METHODS: In total, 446 breast cancer patients and 514 healthy controls were recruited for this...
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