Identification of Novel Loci Shared by Juvenile Idiopathic Arthritis Subtypes Through Integrative Genetic Analysis.

doi:10.1002/art.42129

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Article

Identification of Novel Loci Shared by Juvenile Idiopathic Arthritis Subtypes Through Integrative Genetic Analysis.

Arthritis & rheumatology (Hoboken, N.J.) - 1 Aug 2022

Li Jin, Li Yun R, Glessner Joseph T, Yang Jie, March Michael E, Kao Charlly, Vaccaro Courtney N, Bradfield Jonathan P, Li Junyi, Mentch Frank D, Qu Hui-Qi, Qi Xiaohui, Chang Xiao, Hou Cuiping, Abrams Debra J, Qiu Haijun, Wei Zhi, Connolly John J, Wang Fengxiang, Snyder James, Flatø Berit, Thompson Susan D, Langefeld Carl D, Lie Benedicte A, Munro Jane E, Wise Carol, Sleiman Patrick M A, Hakonarson Hakon

Abstract excerpt

OBJECTIVE: Juvenile idiopathic arthritis (JIA) is the most common chronic immune-mediated joint disease among children and encompasses a heterogeneous group of immune-mediated joint disorders classified into 7 subtypes according to clinical presentation. However, phenotype overlap and biologic evidence suggest a shared mechanistic basis between subtypes. This study was undertaken to systematically investigate...

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Identifiers

PMID: 35347896
DOI: 10.1002/art.42129
PMCID: PMC9542075

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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