Article
Genome-Wide Association Meta-Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci.
Arthritis & rheumatology (Hoboken, N.J.) - 1 Nov 2017
McIntosh Laura A, Marion Miranda C, Sudman Marc, Comeau Mary E, Becker Mara L, Bohnsack John F, Fingerlin Tasha E, Griffin Thomas A, Haas J Peter, Lovell Daniel J, Maier Lisa A, Nigrovic Peter A, Prahalad Sampath, Punaro Marilynn, Rosé Carlos D, Wallace Carol A, Wise Carol A, Moncrieffe Halima, Howard Timothy D, Langefeld Carl D, Thompson Susan D
Abstract excerpt
OBJECTIVE: Juvenile idiopathic arthritis (JIA) is the most common childhood rheumatic disease and has a strong genomic component. To date, JIA genetic association studies have had limited sample sizes, used heterogeneous patient populations, or included only candidate regions. The aim of this study was to identify new associations between JIA patients with oligoarticular disease and those with IgM rheumatoid...
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