Article
Revealing novel genomic insights and therapeutic targets for juvenile idiopathic arthritis through omics.
Rheumatology (Oxford, England) - 1 Sept 2024
Fan Jingxian, Li Xiumei, Yang Jie, Zhang Sipeng, Qu Hui-Qi, Ji Dandan, Glessner Joseph T, Hao Jian, Ding Zhiyong, Wang Nan, Meng Xinyi, Xia Qianghua, Hakonarson Hakon, Wei Wei, Li Jin
Abstract excerpt
BACKGROUND: The genetic architecture of JIA remains only partially comprehended. There is a clear imperative for continued endeavours to uncover insights into the underlying causes of JIA. METHODS: This study encompassed a comprehensive spectrum of endeavours, including conducting a JIA genome-wide association study (GWAS) meta-analysis that incorporated data from 4550 JIA cases and 18 446 controls. We employed...
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