Article
Polyarticular juvenile idiopathic arthritis: insights from genetic studies on disease risk and pathogenesis.
Current opinion in rheumatology - 1 Sept 2026
Okamoto Yuko, Fujisaki Mayuko, Miyamae Takako
Abstract excerpt
PURPOSE OF REVIEW: Genetic and multiomics studies are reshaping our understanding of polyarticular juvenile idiopathic arthritis (JIA) and shifting the field from symptom- and phenotype-based categories toward biologically informed disease definitions. We summarize recent findings on disease risk and pathogenesis while focusing on genetic contributions to disease susceptibility and pathogenic mechanisms. RECENT...
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