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Article

Implications of juvenile idiopathic arthritis genetic risk variants for disease pathogenesis and classification

6 Jun 2019

Abstract excerpt

PURPOSE OF REVIEW: We assess the implications of recent advances in the genetics of juvenile idiopathic arthritis (JIA) for the evolving understanding of inflammatory arthritis in children. RECENT FINDINGS: JIA exhibits prominent genetic associations with the human leukocyte antigen (HLA) region, extending perhaps surprisingly even to the hyperinflammatory systemic JIA category. Some HLA associations resemble...

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PMID: 31169548
DOI: 10.1097/bor.0000000000000637

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