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Article

Detection of disease-causing mutations in prostate cancer by NGS sequencing.

Cell biology international - 1 Jul 2022

Mangolini Alessandra, Rocca Christian, Bassi Cristian, Ippolito Carmelo, Negrini Massimo, Dell'Atti Lucio, Lanza Giovanni, Gafà Roberta, Bianchi Nicoletta, Pinton Paolo, Aguiari Gianluca

Abstract excerpt

Gene mutations may affect the fate of many tumors including prostate cancer (PCa); therefore, the research of specific mutations associated with tumor outcomes might help the urologist to identify the best therapy for PCa patients such as surgical resection, adjuvant therapy or active surveillance. Genomic DNA (gDNA) was extracted from 48 paraffin-embedded PCa samples and normal paired tissues. Next, gDNA was...

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Identifiers

PMID: 35347810
DOI: 10.1002/cbin.11803
PMCID: PMC9320837

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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