Article
Mutation detection in formalin-fixed prostate cancer biopsies taken at the time of diagnosis using next-generation DNA sequencing.
Journal of clinical pathology - 1 Mar 2015
Manson-Bahr David, Ball Richard, Gundem Gunes, Sethia Krishna, Mills Robert, Rochester Mark, Goody Victoria, Anderson Elizabeth, O'Meara Sarah, Flather Marcus, Keeling Matthew, Yazbek-Hanna Marcelino, Hurst Rachel, Curley Helen, Clark Jeremy, Brewer Daniel S, McDermott Ultan, Cooper Colin
Abstract excerpt
AIMS: Assessing whether next-generation DNA sequencing (NGS) can be used to screen prostate cancer for multiple gene alterations in men routinely diagnosed with this disease and/or who are entered into clinical trials. Previous studies are limited and have reported only low success rates. METHODS...
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