Article
Somatic and Germline Variants Affect Prognosis and Susceptibility in Prostate Cancer.
Anticancer research - 1 Jul 2023
Rocca Christian, Rocca Giulia, Zampieri Pietro, Dell'atti Lucio, Bianchi Nicoletta, Ippolito Carmelo, Aguiari Gianluca
Abstract excerpt
BACKGROUND/AIM: Prostate cancer (PCa) is one of the most common tumors in men accounting for the 7.3% of all cancer-associated diseases in 2020. In advanced stage, this pathology is a lethal disease and is the fifth cause of cancer death in men worldwide. The diagnosis of PCa is performed by prostate-specific antigen (PSA) detection combined with direct rectal examination (DRE). However, high PSA levels can be...
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