Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Optimized outcome prediction of oncogenetic mutations in non-early T-cell precursor acute lymphoblastic leukemia.

Immunobiology - 1 May 2022

Peng Li-Jun, Wang Si-Si, Guo Shan-Shan, Zhang Jiao-Jiao, Liu Yuan-Fang, Rousseaux Sophie, Khochbin Saadi, Chen Bing, Wang Jin, Mi Jian-Qing

Abstract excerpt

BACKGROUND: Early biomarkers allowing effective treatment stratification in adult T-cell acute lymphoblastic leukemia (T-ALL) patients remain elusive. MATERIALS AND METHODS: The mutation spectrum of 116T-ALL adult patients enrolled in the Shanghai Institute of Hematology (SIH)-based hospital network or Multicenter Hematology-Oncology Protocols Evaluation System (M-HOPES) in China were studied by using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to China
Share to F-Box-WD Repeat-Containing Protein 7

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Share to Prognosis

Source

Identifiers

PMID: 35279479
DOI: 10.1016/j.imbio.2022.152205

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Optimized outcome prediction of oncogenetic mutations in non-early T-cell precursor acute lymphoblastic leukemia.PMID 35279479Read ↗

Toward a NOTCH1/FBXW7/RAS/PTEN-based oncogenetic risk classification of adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic Leukemia study.Semantic proximity Read ↗

Genetic mutational profiling analysis of T cell acute lymphoblastic leukemia reveal mutant FBXW7 as a prognostic indicator for inferior survival.Semantic proximity Read ↗

NGS-based stratification refines the risk stratification in T-ALL and identifies a very-high-risk subgroup of patients.Semantic proximity Read ↗

Clinical and molecular characterization of early T-cell precursor leukemia: a high-risk subgroup in adult T-ALL with a high frequency of FLT3 mutationsSemantic proximity Read ↗

The RAS-signaling-pathway-mutation-related prognosis in B-cell acute lymphoblastic leukemia: A report from South China children's leukemia group.Semantic proximity Read ↗

Inside the biology of early T-cell precursor acute lymphoblastic leukemia: the perfect trickSemantic proximity Read ↗

Spectrum of somatic mutations detected by targeted next-generation sequencing and their prognostic significance in adult patients with acute lymphoblastic leukemiaSemantic proximity Read ↗

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.Semantic proximity Read ↗

Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes.Semantic proximity Read ↗

Oncogenetic mutations combined with MRD improve outcome prediction in pediatric T-cell acute lymphoblastic leukemia.Semantic proximity Read ↗

Integrated Genomic Analyses Identify High-Risk Factors and Actionable Targets in T-Cell Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Characteristics of Molecular Genetic Mutations and Their Correlation with Prognosis in Adolescent and Adult Patients with Acute Lymphoblastic Leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.