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Inside the biology of early T-cell precursor acute lymphoblastic leukemia: the perfect trick

1 Dec 2021

Abstract excerpt

Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) is a rare, distinct subtype of T-ALL characterized by genomic instability, a dismal prognosis and refractoriness to standard chemotherapy. Since its first description in 2009, the expanding knowledge of its intricate biology has led to the definition of a stem cell leukemia with a combined lymphoid-myeloid potential: the perfect trick. Several studies...

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PMID: 34930475
DOI: 10.1186/s40364-021-00347-z

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