Article
Loss of calsyntenin paralogs disrupts interneuron stability and mouse behavior.
Molecular brain - 12 Mar 2022
Mori Keita, Koebis Michinori, Nakao Kazuki, Kobayashi Shizuka, Kiyama Yuji, Watanabe Masahiko, Manabe Toshiya, Iino Yuichi, Aiba Atsu
Abstract excerpt
Calsyntenins (CLSTNs) are important synaptic molecules whose molecular functions are not fully understood. Although mutations in calsyntenin (CLSTN) genes have been associated with psychiatric disorders in humans, their function is still unclear. One of the reasons why the function of CLSTNs in the nervous system has not been clarified is the functional redundancy among the three paralogs. Therefore, to...
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