Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpression of piccolo C2A domain induces depression-like behavior in mice.

Neuroreport - 29 Dec 2010

Furukawa-Hibi Yoko, Nitta Atsumi, Fukumitsu Hidefumi, Somiya Hitomi, Furukawa Shoei, Nabeshima Toshitaka, Yamada Kiyofumi

Abstract excerpt

Piccolo is one of the components of the active zone at chemical synapses and regulates the transport of synaptic vesicles. The piccolo C2A domain is an important calcium sensor and binds with phosphatidylinositol or synaptotagmin-1. Recently, clinical studies suggested that a single nucleotide po...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytoskeletal Proteins
Share to Depressive Disorder
Share to Disease Models, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred C57BL

Share to Mice, Transgenic

Share to Neuropeptides

Share to Peptide Fragments

Share to Protein Structure, Tertiary

Source

Identifiers

PMID: 20980930
DOI: 10.1097/WNR.0b013e3283411685

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20980930-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overexpression of piccolo C2A domain induces depression-like behavior in mice.PMID 20980930Read ↗

Limb-clasping, cognitive deficit and increased vulnerability to kainic acid-induced seizures in neuronal glycosylphosphatidylinositol deficiency mouse models.Semantic proximity Read ↗

Zic2 hypomorphic mutant mice as a schizophrenia model and ZIC2 mutations identified in schizophrenia patients.Semantic proximity Read ↗

Protrudin-deficient mice manifest depression-like behavior with abnormalities in activity, attention, and cued fear-conditioning.Semantic proximity Read ↗

Limb-clasping, cognitive deficit and increased vulnerability to kainic acid - induced seizures in neuronal GPI anchor deficiency mouse modelsSemantic proximity Read ↗

Identification and immunocytochemical characterization of Piccolino, a novel Piccolo splice variant selectively expressed at sensory ribbon synapses of the eye and ear.Semantic proximity Read ↗

Hippocampal SPARC regulates depression-related behavior.Semantic proximity Read ↗

Modulation ofTcf7l2 expression alters behavior in mice.Semantic proximity Read ↗

Behavioral and pharmacological phenotypes of brain-specific diacylglycerol kinase δ-knockout mice.Semantic proximity Read ↗

Levetiracetam-mediated emotional behavior in heterozygous rolling Nagoya Ca(V)2.1 channel mutant mice.Semantic proximity Read ↗

Depression-resistant Phenotype in Mice Overexpressing Regulator of G Protein Signaling 8 (RGS8).Semantic proximity Read ↗

Effects of chronic sleep restriction on the neuro-phenotypes of Ctnnd2 knockout mice.Semantic proximity Read ↗

Anxiety- and depressive-like behaviors in olfactory deficient Cnga2 knockout mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.