Article
A conserved function of C. elegans CASY-1 calsyntenin in associative learning.
PloS one - 1 Jan 2009
Hoerndli Frédéric J, Walser Michael, Fröhli Hoier Erika, de Quervain Dominique, Papassotiropoulos Andreas, Hajnal Alex
Abstract excerpt
BACKGROUND: Whole-genome association studies in humans have enabled the unbiased discovery of new genes associated with human memory performance. However, such studies do not allow for a functional or causal testing of newly identified candidate genes. Since polymorphisms in Calsyntenin 2 (CLSTN2) showed a significant association with episodic memory performance in humans, we tested the C. elegans CLSTN2 ortholog...
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