Article
Impaired long-term potentiation and long-term memory deficits in xCT-deficient sut mice.
Bioscience reports - 1 Jun 2012
Li Yan, Tan Zhibing, Li Zhigang, Sun Zhongsheng, Duan Shumin, Li Wei
Abstract excerpt
xCT is the functional subunit of the cystine/glutamate antiporter system xc-, which exchanges intracellular glutamate with extracellular cystine. xCT has been reported to play roles in the maintenance of intracellular redox and ambient extracellular glutamate, which may affect neuronal function. To assess a potential role of xCT in the mouse hippocampus, we performed fear conditioning and passive avoidance for...
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