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Article

Comprehensive behavioral phenotyping of calpastatin-knockout mice.

Molecular brain - 15 Sept 2008

Nakajima Ryuichi, Takao Keizo, Huang Shu-Ming, Takano Jiro, Iwata Nobuhisa, Miyakawa Tsuyoshi, Saido Takaomi C

Abstract excerpt

BACKGROUND: Calpastatin is an endogenous inhibitor of calpain, intracellular calcium-activated protease. It has been suggested to be involved in molecular mechanisms of long-term plasticity and excitotoxic pathways. However, functions of calpastatin in vivo are still largely unknown. To examine the physiological roles of calpastatin, we subjected calpastatin-knockout mice to a comprehensive behavioral test...

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Identifiers

PMID: 18803809
DOI: 10.1186/1756-6606-1-7
PMCID: PMC2561015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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