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Article

Calsyntenin-1 docks vesicular cargo to kinesin-1.

Molecular biology of the cell - 1 Aug 2006

Konecna Anetta, Frischknecht Renato, Kinter Jochen, Ludwig Alexander, Steuble Martin, Meskenaite Virginia, Indermühle Martin, Engel Marianne, Cen Chuan, Mateos José-Maria, Streit Peter, Sonderegger Peter

Abstract excerpt

We identified a direct interaction between the neuronal transmembrane protein calsyntenin-1 and the light chain of Kinesin-1 (KLC1). GST pulldowns demonstrated that two highly conserved segments in the cytoplasmic domain of calsyntenin-1 mediate binding to the tetratricopeptide repeats of KLC1. A complex containing calsyntenin-1 and the Kinesin-1 motor was isolated from developing mouse brain and immunoelectron...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 16760430
DOI: 10.1091/mbc.e06-02-0112
PMCID: PMC1525238

Genes

KLC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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