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Article

DSTYK kinase domain ablation impaired the mice capabilities of learning and memory in water maze test.

International journal of clinical and experimental pathology - 1 Jan 2014

Li Kui, Liu Ji-Wei, Zhu Zhi-Chuan, Wang Hong-Tao, Zu Yong, Liu Yong-Jie, Yang Yan-Hong, Xiong Zhi-Qi, Shen Xu, Chen Rui, Zheng Jing, Hu Ze-Lan

Abstract excerpt

DSTYK (Dual serine/threonine and tyrosine protein kinase) is a putative dual Ser/Thr and Tyr protein kinase with unique structural features. It is proposed that DSTYK may play important roles in brain because of its high expression in most brain areas. In the present study, a DSTYK knockout (KO) mouse line with the ablation of C-terminal of DSTYK including the kinase domain was generated to study the...

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Identifiers

PMID: 25400726
PMCID: PMC4230056

Genes

DSTYK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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