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Article

Assessing the causal associations of obstructive sleep apnea with serum uric acid levels and gout: a bidirectional two-sample Mendelian randomization study.

Seminars in arthritis and rheumatism - 1 Dec 2022

Zeng Zhen, Jin Ting, Ni Jing, Huang Li, Xie Yanqing, He Wenming, Zhang Lina, Ding Changhai, Cen Han

Abstract excerpt

OBJECTIVE: Multiple observational studies have reported the close associations of obstructive sleep apnea (OSA) with serum uric acid (SUA) levels and gout. However, the causal nature and direction remains unclear. METHODS: A bidirectional two-sample Mendelian randomization (MR) study was performed, based on publicly available genome-wide association studies (GWAS) summary statistics, to investigate whether OSA is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36126568
DOI: 10.1016/j.semarthrit.2022.152095

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