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Article

The causal associations of serum uric acid levels and gout with the risk of acute pancreatitis: A bidirectional Mendelian randomization study.

Medicine - 3 Jul 2026

Lin YiQing, Zheng QianWen, Peng LianGong, Chen Mo, Zhang Chao, Chen Shuifang

Abstract excerpt

This study investigates the causal links between serum uric acid (UA), gout, and the risk of acute pancreatitis (AP) using a bidirectional 2-sample Mendelian randomization analysis of genome-wide association studies data. The primary inverse variance weighted method indicated that genetically predicted higher serum UA levels are causally associated with an increased risk of AP (odds ratio [OR] = 1.194, 95%...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42410834
DOI: 10.1097/MD.0000000000049605
PMCID: PMC13336928

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