Article
Global DNA methylation profiling reveals chromosomal instability in IDH-mutant astrocytomas.
Acta neuropathologica communications - 9 Mar 2022
Liu Yan, Sathe Adwait Amod, Abdullah Kalil G, McBrayer Samuel K, Adams Steven H, Brenner Andrew J, Hatanpaa Kimmo J, Viapiano Mariano S, Xing Chao, Walker Jamie M, Richardson Timothy E
Abstract excerpt
Diffusely infiltrating gliomas are among the most common central nervous system tumors in adults. Over the past decade, the subcategorization of these tumors has changed to include both traditional histologic features and more recently identified molecular factors. However, one molecular feature that has yet to be integrated is the presence/absence of chromosomal instability (CIN). Herein, we use global...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.