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Article

The stalk domain of SARS-CoV-2 NSP13 is essential for its helicase activity.

Biochemical and biophysical research communications - 23 Apr 2022

Yue Kun, Yao Bin, Shi Yingchao, Yang Yang, Qian Zhaohui, Ci Yali, Shi Lei

Abstract excerpt

COVID-19, caused by SARS-CoV-2, has been spreading worldwide for more than two years and has led to immense challenges to human health. Despite the great efforts that have been made, our understanding of SARS-CoV-2 is still limited. The viral helicase, NSP13 is an important enzyme involved in SARS-CoV-2 replication and transcription. Here we highlight the important role of the stalk domain in the enzymatic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35245742
DOI: 10.1016/j.bbrc.2022.02.068
PMCID: PMC8864812

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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