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Article

What a twist: structural biology of the SARS-CoV-2 helicase nsp13

2023-10-02

Abstract excerpt

SARS-CoV-2 nsp13 is a multifunctional helicase from helicase superfamily 1B. It unwinds the viral RNA genome for replication and is thought to play a role in 5’ mRNA capping to produce mature mRNA using its triphosphatase activity. The sequence and structure are highly conserved in nidovirales and the protein is essential to the viral infection cycle, acting as a standalone enzyme and in conjunction with other SAR...

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Literature Corpus work
04c8e6e6-3177-5616-91e4-e1526424fffd
DOI
10.1080/0889311x.2024.2309494
Open publication

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What a twist: structural biology of the SARS-CoV-2 helicase nsp13DOI 10.1080/0889311x.2024.2309494
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