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Host DDX Helicases as Possible SARS-CoV-2 Proviral Factors: A Structural Overview of Their Hijacking Through Multiple Viral Proteins

10 Dec 2020

Abstract excerpt

As intracellular parasites, viruses hijack the host cell metabolic machinery for their replication. Among other cellular proteins, the DEAD-box (DDX) RNA helicases have been shown to be hijacked by coronaviruses and to participate in essential DDX-mediated viral replication steps. Human DDX RNA helicases play essential roles in a broad array of biological processes and serve multiple roles at the virus-host...

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PMID: 33381492
DOI: 10.3389/fchem.2020.602162

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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