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Article

Loss of MIG-6 results in endometrial progesterone resistance via ERBB2

1 Mar 2022

Abstract excerpt

Abstract Female subfertility is highly associated with endometriosis. Endometrial progesterone resistance is suggested as a crucial element in the development of endometrial diseases. We report that MIG-6 is downregulated in the endometrium of infertile women with endometriosis and in a non-human primate model of endometriosis. We find ERBB2 overexpression in the endometrium of uterine-specific Mig-6 knockout...

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PMID: 35232969
DOI: 10.1038/s41467-022-28608-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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