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Article

Generation of a Mig-6 conditional null allele.

Genesis (New York, N.Y. : 2000) - 1 Nov 2007

Jin Nili, Gilbert Jennifer L, Broaddus Russell R, Demayo Francesco J, Jeong Jae-Wook

Abstract excerpt

Mitogen-inducible gene 6 (Mig-6) is a stress-induced gene that serves as a negative regulator of epidermal growth factor (EGF) signaling and acts as a tumor suppressor. Ablation of Mig-6 results in a significant percentage of embryo lethality as well as abnormalities in multiple tissues. To under...

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Identifiers

PMID: 17987665
DOI: 10.1002/dvg.20348

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17987665-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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