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Article

COUP-TFII Mediates Progesterone Regulation of Uterine Implantation by Controlling ER Activity

14 Jun 2007

Abstract excerpt

Progesterone and estrogen are critical regulators of uterine receptivity. To facilitate uterine remodeling for embryo attachment, estrogen activity in the uterine epithelia is attenuated by progesterone; however, the molecular mechanism by which this occurs is poorly defined. COUP-TFII (chicken ovalbumin upstream promoter transcription factor II; also known as NR2F2), a member of the nuclear receptor superfamily,...

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PMID: 17590085
DOI: 10.1371/journal.pgen.0030102

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