Article

Deletion of <i>Gremlin-2</i> alters estrous cyclicity and disrupts female fertility in mice

2020-10-01

Abstract excerpt

Members of the differential screening-selected gene aberrative in neuroblastoma (DAN) protein family are developmentally conserved extracellular binding proteins that antagonize bone morphogenetic protein (BMP) signaling. This protein family includes the Gremlin proteins, GREM1 and GREM2, which are known to have key functions during embryogenesis and adult physiology. While BMPs play essential roles in adult femal...

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Literature Corpus work: 9fa18529-adac-5263-b4f6-2c7569c74e43
DOI: 10.1101/2020.10.01.322818

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