Article
[Mutational spectrum and its prognostic significance in childhood acute lymphoblastic leukemia based on next-generation sequencing technology].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 14 Jan 2022
Zheng Y Z, Zheng H, Chen Z S, Hua X L, Le S H, Li J, Hu J D
Abstract excerpt
Objective: This study analyzed the correlation between genetic mutation and prognostic significance in childhood acute lymphoblastic leukemia (ALL) . Methods: Targeted exome by next-generation sequencing (NGS) technology was used to carry out molecular profiling of untreated 141 children with ALL in Fujian Medical University Union Hospital from November 2016 to December 2019. Correlation of genetic features and...
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