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[Clinical Study on the Relationship between Gene Mutation Profile and Prognosis in Pediatric Acute Lymphocyte Leukemia].

Zhongguo shi yan xue ye xue za zhi - 1 Feb 2023

Chen Yan, Qi Shan-Shan, Ding Li-Li, DU Yu, Song Na, Wang Zhuo, Yang Li, Sun Ming, Xiong Hao

Abstract excerpt

OBJECTIVE: To analyze the gene mutation profile in children with acute lymphocyte leukemia (ALL) and to explore its prognostic significance. METHODS: Clinical data of 249 primary pediatric ALL patients diagnosed and treated in the Department of Hematological Oncology of Wuhan Children's Hospital from January 2018 to December 2021 were analyzed retrospectively. Next-generation sequencing (NGS) was used to obtain...

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Cell Cycle Proteins
Lymphocytes
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins p21(ras)

Ubiquitin-Protein Ligases

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PMID: 36765471
DOI: 10.19746/j.cnki.issn.1009-2137.2023.01.003

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