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An immunogenetic investigation of 30 autoimmune and autoinflammatory diseases and their links to psychiatric disorders in a nationwide sample.

Immunology - 1 Apr 2023

Nudel Ron, Allesøe Rosa Lundbye, Werge Thomas, Thompson Wesley K, Rasmussen Simon, Benros Michael E

Abstract excerpt

Autoimmune and autoinflammatory diseases (AIIDs) involve a deficit in an individual's immune system function, whereby the immune reaction is directed against self-antigens. Many AIIDs have a strong genetic component, but they can also be triggered by environmental factors. AIIDs often have a highly negative impact on the individual's physical and mental wellbeing. Understanding the genetic underpinning of AIIDs...

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PMID: 36273265
DOI: 10.1111/imm.13597

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