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Article

The MHC locus and genetic susceptibility to autoimmune and infectious diseases.

Genome biology - 27 Apr 2017

Matzaraki Vasiliki, Kumar Vinod, Wijmenga Cisca, Zhernakova Alexandra

Abstract excerpt

In the past 50 years, variants in the major histocompatibility complex (MHC) locus, also known as the human leukocyte antigen (HLA), have been reported as major risk factors for complex diseases. Recent advances, including large genetic screens, imputation, and analyses of non-additive and epistatic effects, have contributed to a better understanding of the shared and specific roles of MHC variants in different...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28449694
DOI: 10.1186/s13059-017-1207-1
PMCID: PMC5406920

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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