Article
Breast Cancer Incidence After Risk-Reducing Salpingo-Oophorectomy in BRCA1 and BRCA2 Mutation Carriers.
Cancer prevention research (Philadelphia, Pa.) - 1 Nov 2012
Fakkert Ingrid E, Mourits Marian J E, Jansen Liesbeth, van der Kolk Dorina M, Meijer Kees, Oosterwijk Jan C, van der Vegt Bert, Greuter Marcel J W, de Bock Geertruida H
Abstract excerpt
Premenopausal risk-reducing salpingo-oophorectomy (RRSO) in BRCA1/2 mutation carriers effectively reduces ovarian cancer risk, but also reduces breast cancer risk. Breast cancer risk reductions up to 50% have been reported for both BRCA1 and BRCA2 mutation carriers, but recent prospective studies were not able to reproduce this finding for BRCA1 mutation carriers. Breast cancer incidence after RRSO was assessed...
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