Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Variety of Nucleic Acid Species Are Sensed by cGAS, Implications for Its Diverse Functions

4 Feb 2022

Abstract excerpt

activation of the key downstream adaptor protein stimulator of interferon genes (STING). This is the most classic biological function of the cGAS-STING signaling pathway and is critical for preventing pathogenic microorganism invasion. In addition, cGAS can interact with various types of nucleic acids, including cDNA, DNA : RNA hybrids, and circular RNA, to contribute to a diverse set of biological functions. An...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Inflammasome and immune disorders
Share to interferon and immune responses
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35185917
DOI: 10.3389/fimmu.2022.826880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Variety of Nucleic Acid Species Are Sensed by cGAS, Implications for Its Diverse FunctionsPMID 35185917Read ↗

Significance of the cGAS-STING Pathway in Health and DiseaseSemantic proximity Read ↗

Research Advances in How the cGAS-STING Pathway Controls the Cellular Inflammatory ResponseSemantic proximity Read ↗

The regulation of cGAS-STING signaling by RNA virus-derived componentsSemantic proximity Read ↗

Function and regulation of cGAS-STING signaling in infectious diseasesSemantic proximity Read ↗

The multifaceted functions of cGASSemantic proximity Read ↗

Beyond DNA sensing: expanding the role of cGAS/STING in immunity and diseasesSemantic proximity Read ↗

The cGAS-STING Pathway: A Promising Immunotherapy TargetSemantic proximity Read ↗

The triggers of the cGAS-STING pathway and the connection with inflammatory and autoimmune diseasesSemantic proximity Read ↗

IUPHAR ECR review: The cGAS-STING pathway: Novel functions beyond innate immune and emerging therapeutic opportunitiesSemantic proximity Read ↗

The cGAS-STING pathway in viral infections: a promising link between inflammation, oxidative stress and autophagySemantic proximity Read ↗

How the Innate Immune DNA Sensing cGAS–STING Pathway Is Involved in AutophagySemantic proximity Read ↗

Roles of the cGAS-STING Pathway in Cancer Immunosurveillance and ImmunotherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.