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Article

A specialist-generalist framework for epithelial-mesenchymal plasticity in cancer.

Trends in cancer - 1 May 2022

Cook David P, Wrana Jeffrey L

Abstract excerpt

Epithelial-mesenchymal plasticity (EMP) reflects the capacity of cells to interconvert between epithelial and mesenchymal phenotypes. In cancer, these dynamics ultimately contribute to disease progression. Despite decades of study, a consistent molecular definition of this plasticity remains elusive because of its inherent variability. The advent of quantitative single-cell biology is unveiling unexpected...

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Identifiers

PMID: 35183479
DOI: 10.1016/j.trecan.2022.01.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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