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Article

The epithelial-mesenchymal plasticity landscape: principles of design and mechanisms of regulation.

Nature reviews. Genetics - 1 Sept 2023

Haerinck Jef, Goossens Steven, Berx Geert

Abstract excerpt

Epithelial-mesenchymal plasticity (EMP) enables cells to interconvert between several states across the epithelial-mesenchymal landscape, thereby acquiring hybrid epithelial/mesenchymal phenotypic features. This plasticity is crucial for embryonic development and wound healing, but also underlies the acquisition of several malignant traits during cancer progression. Recent research using systems biology and...

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Identifiers

PMID: 37169858
DOI: 10.1038/s41576-023-00601-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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