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Article

Cellular and molecular mechanisms of plasticity in cancer.

Trends in cancer - 1 Sept 2022

Torborg Stefan R, Li Zhuxuan, Chan Jason E, Tammela Tuomas

Abstract excerpt

Cancer cells are plastic - they can assume a wide range of distinct phenotypes. Plasticity is integral to cancer initiation and progression, as well as to the emergence and maintenance of intratumoral heterogeneity. Furthermore, plastic cells can rapidly adapt to and evade therapy, which poses a challenge for effective cancer treatment. As such, targeting plasticity in cancer holds tremendous promise. Yet, the...

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Identifiers

PMID: 35618573
DOI: 10.1016/j.trecan.2022.04.007
PMCID: PMC9388572

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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