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Article

Mutations in the three largest subunits of yeast RNA polymerase II that affect enzyme assembly.

Molecular and cellular biology - 1 Sept 1991

Kolodziej P A, Young R A

Abstract excerpt

Mutations in the three largest subunits of yeast RNA polymerase II (RPB1, RPB2, and RPB3) were investigated for their effects on RNA polymerase II structure and assembly. Among 23 temperature-sensitive mutations, 6 mutations affected enzyme assembly, as assayed by immunoprecipitation of epitope-tagged subunits. In all six assembly mutants, RNA polymerase II subunits synthesized at the permissive temperature were...

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Identifiers

PMID: 1715023
DOI: 10.1128/mcb.11.9.4669-4678.1991
PMCID: PMC361357

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