Mutations in the three largest subunits of yeast RNA polymerase II that affect enzyme assembly.

doi:10.1128/mcb.11.9.4669-4678.1991

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Article

Mutations in the three largest subunits of yeast RNA polymerase II that affect enzyme assembly.

Molecular and cellular biology - 1 Sept 1991

Kolodziej P A, Young R A

Abstract excerpt

Mutations in the three largest subunits of yeast RNA polymerase II (RPB1, RPB2, and RPB3) were investigated for their effects on RNA polymerase II structure and assembly. Among 23 temperature-sensitive mutations, 6 mutations affected enzyme assembly, as assayed by immunoprecipitation of epitope-t...

Topics

Amino Acid Sequence
Epitopes
Molecular Sequence Data
Mutation
Phenotype
Precipitin Tests
RNA Polymerase II
Saccharomyces cerevisiae
Temperature

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