Article
CRISPR-Based Screening for Stress Response Factors in Mammalian Cells.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2022
Guo Xiaoyan, Kampmann Martin
Abstract excerpt
In the presence of different physiological and environmental stresses, cells rapidly initiate stress responses to re-establish cellular homeostasis. Stress responses usually orchestrate both transcriptional and translational programs via distinct mechanisms. With the advance of transcriptomics and proteomics technologies, transcriptional and translational outputs to a particular stress condition have become...
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