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Article

Role of the Transcription Factor FOSL1 in Organ Development and Tumorigenesis.

International journal of molecular sciences - 28 Jan 2022

Sobolev Vladimir V, Khashukoeva Asiat Z, Evina Olga E, Geppe Natalia A, Chebysheva Svetlana N, Korsunskaya Irina M, Tchepourina Ekaterina, Mezentsev Alexandre

Abstract excerpt

The transcription factor FOSL1 plays an important role in cell differentiation and tumorigenesis. Primarily, FOSL1 is crucial for the differentiation of several cell lineages, namely adipocytes, chondrocytes, and osteoblasts. In solid tumors, FOSL1 controls the progression of tumor cells through the epithelial-mesenchymal transformation. In this review, we summarize the available data on FOSL1 expression,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Neoplastic

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Share to Proto-Oncogene Proteins c-fos

Source

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Identifiers

PMID: 35163444
DOI: 10.3390/ijms23031521
PMCID: PMC8835756

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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