Article

Mapping Interactome Networks of FOSL1 and FOSL2 in Human Th17 Cells

2021-05-14

Abstract excerpt

<h4>ABSTRACT</h4> Dysregulated function of Th17 cells has implications in immunodeficiencies and autoimmune disorders. Th17 cell-differentiation is orchestrated by a complex network of transcription factors, including several members of the activator protein (AP-1) family. Among these, FOSL1 and FOSL2 influence the effector responses of Th17 cells. However, the molecular mechanisms underlying these functions are...

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Literature Corpus work: 9c77a54f-b406-5628-a603-ca4b34973c3a
DOI: 10.1101/2021.05.12.443731

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