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Role of Fra-2 in cancer

16 Dec 2023

Abstract excerpt

Fos-related antigen-2 (Fra-2) is the most recently discovered member of the Fos family and, by dimerizing with Jun proteins, forms the activator protein 1 (AP-1) transcription factor. By inducing or repressing the transcription of several target genes, Fra-2 is critically involved in the modulation of cell response to a variety of extracellular stimuli, stressors and intracellular changes. In physiological...

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PMID: 38104183
DOI: 10.1038/s41418-023-01248-4

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