Article
Systematic Evaluation of HLA-G 3'Untranslated Region Variants in Locally Advanced, Non-Metastatic Breast Cancer Patients: UTR-1, 2 or UTR-4 are Predictors for Therapy and Disease Outcome.
Frontiers in immunology - 1 Jan 2021
Rebmann Vera, Schwich Esther, Michita Rafael Tomoya, Grüntkemeier Lisa, Bittner Ann-Kathrin, Rohn Hana, Horn Peter A, Hoffmann Oliver, Kimmig Rainer, Kasimir-Bauer Sabine
Abstract excerpt
Despite major improvements in diagnostics and therapy in early as well as in locally advanced breast cancer (LABC), metastatic relapse occurs in about 20% of patients, often explained by early micro-metastatic spread into bone marrow by disseminated tumor cells (DTC). Although neoadjuvant chemotherapy (NACT) has been a successful tool to improve overall survival (OS), there is growing evidence that various...
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