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Article

HLA-G 3'UTR Polymorphisms Are Linked to Susceptibility and Survival in Spanish Gastric Adenocarcinoma Patients.

Frontiers in immunology - 1 Jan 2021

Vaquero-Yuste Christian, Juarez Ignacio, Molina-Alejandre Marta, Molanes-López Elisa María, López-Nares Adrián, Suárez-Trujillo Fabio, Gutiérrez-Calvo Alberto, López-García Adela, Lasa Inmaculada, Gómez Remedios, Fernández-Cruz Eduardo, Rodrígez-Sainz Carmen, Arnaiz-Villena Antonio, Martín-Villa José Manuel

Abstract excerpt

HLA-G is a non-classical class I HLA molecule that induces tolerance by acting on receptors of both innate and adaptive immune cells. When overexpressed in tumors, limits surveillance by the immune system. The HLA-G gene shows several polymorphisms involved in mRNA and protein levels. We decided to study the implication of two polymorphisms (rs371194629; 14bp INS/DEL and rs1063320; +3142 C/G) in paired tissue...

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Source

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Identifiers

PMID: 34557189
DOI: 10.3389/fimmu.2021.698438
PMCID: PMC8453083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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