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Article

Genetic 3'UTR variations and clinical factors significantly contribute to survival prediction and clinical response in breast cancer patients.

Scientific reports - 31 Mar 2020

Pamuła-Piłat Jolanta, Tęcza Karolina, Kalinowska-Herok Magdalena, Grzybowska Ewa

Abstract excerpt

The study describes a relationship between the 3'UTR variants, clinicopathological parameters and response to chemotherapy. We analyzed 33 germline polymorphisms in 3'UTRs of ADME genes in 305 breast cancer women treated with FAC regime. Clinical endpoints of this study were: overall survival (OS), progression-free survival (PFS), recurrence-free survival (RFS) and overall response defined as treatment...

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Identifiers

PMID: 32235849
DOI: 10.1038/s41598-020-62662-z
PMCID: PMC7109149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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