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Article

Rare BRCA1 haplotypes including 3'UTR SNPs associated with breast cancer risk.

Cell cycle (Georgetown, Tex.) - 1 Jan 2011

Pelletier Cory, Speed William C, Paranjape Trupti, Keane Katie, Blitzblau Rachel, Hollestelle Antoinette, Safavi Kyan, van den Ouweland Ans, Zelterman Daniel, Slack Frank J, Kidd Kenneth K, Weidhaas Joanne B

Abstract excerpt

Genetic markers identifying women at an increased risk of developing breast cancer exist, yet the majority of inherited risk remains elusive. While numerous BRCA1 coding sequence mutations are associated with breast cancer risk, BRCA1 mutations account for less then 5% of breast cancer risk. Since 3' untranslated region (3'UTR) polymorphisms disrupting microRNA (miRNA) binding can be functional and can act as...

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Identifiers

PMID: 21191178
DOI: 10.4161/cc.10.1.14359
PMCID: PMC3048078

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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