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HLA-G high-expressor 3'UTR markers are linked to gastric cancer development and survival.

Cancer immunology, immunotherapy : CII - 16 Nov 2024

Vaquero-Yuste Christian, Juarez Ignacio, Molina-Alejandre Marta, Molanes-López Elisa María, Gutiérrez-Calvo Alberto, López-García Adela, Lasa Inmaculada, Gómez Remedios, Arnaiz-Villena Antonio, Martín-Villa Jose Manuel

Abstract excerpt

Gastric cancer ranks fifth in both world prevalence and lethality, with a 5-year survival of less than 30%. HLA-G, a non-classical class I HLA gene, has emerged as a potential marker for cancer susceptibility and prognosis due to its immunomodulatory properties. Its level of expression is regulated by polymorphisms in the 3' untranslated region (3'UTR) polymorphisms, which form various combined haplotypes (UTR-1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39549048
DOI: 10.1007/s00262-024-03771-w
PMCID: PMC11569108

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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