Article
Elevated sHLA-G plasma levels post chemotherapy combined with ILT-2 rs10416697C allele status of the sHLA-G-related receptor predict poorest disease outcome in early triple-negative breast cancer patients.
Frontiers in immunology - 1 Jan 2023
Hoffmann Oliver, Wormland Sebastian, Bittner Ann-Kathrin, Hölzenbein Julian, Schwich Esther, Schramm Sabine, Rohn Hana, Horn Peter A, Kimmig Rainer, Kasimir-Bauer Sabine, Rebmann Vera
Abstract excerpt
Introduction: Triple negative breast cancer (TNBC) shows an aggressive growing and spreading behavior and has limited treatment options, often leading to inferior disease outcome. Therefore, surrogate markers are urgently needed to identify patients at high risk of recurrence and more importantly, to identify additional therapeutic targets enabling further treatment options. Based on the key role of the...
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