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American Heart Association's Life's Simple 7: Lifestyle Recommendations, Polygenic Risk, and Lifetime Risk of Coronary Heart Disease.

Circulation - 15 Mar 2022

Hasbani Natalie R, Ligthart Symen, Brown Michael R, Heath Adam S, Bebo Allison, Ashley Kellan E, Boerwinkle Eric, Morrison Alanna C, Folsom Aaron R, Aguilar David, de Vries Paul S

Abstract excerpt

BACKGROUND: Understanding the effect of lifestyle and genetic risk on the lifetime risk of coronary heart disease (CHD) is important to improving public health initiatives. Our objective was to quantify remaining lifetime risk and years free of CHD according to polygenic risk and the American Heart Association's Life's Simple 7 (LS7) guidelines in a population-based cohort study. METHODS: Our analysis included...

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Identifiers

PMID: 35094551
DOI: 10.1161/CIRCULATIONAHA.121.053730
PMCID: PMC8912968

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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