SIRT1 rs7896005 polymorphism affects major vascular outcomes, not all-cause mortality, in Caucasians with type 2 diabetes: A 13-year observational study.

doi:10.1002/dmrr.3523

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SIRT1 rs7896005 polymorphism affects major vascular outcomes, not all-cause mortality, in Caucasians with type 2 diabetes: A 13-year observational study.

Diabetes/metabolism research and reviews - 1 May 2022

Dardano Angela, Lucchesi Daniela, Garofolo Monia, Gualdani Elisa, Falcetta Pierpaolo, Sancho Bornez Veronica, Francesconi Paolo, Del Prato Stefano, Penno Giuseppe

Abstract excerpt

AIMS: SIRT1 exerts effects on ageing and lifespan, as well cardiovascular (CV) disease risk. SIRT1 gene is very polymorph with a few tagging single nucleotide polymorphisms (SNPs) so far identified. Some SNPs, including rs7896005, were associated with type 2 diabetes (T2DM). We aimed to ascertain whether this SNP may be associated with CV disease at baseline as well with these same outcomes and all-cause...

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Identifiers

PMID: 35092334
DOI: 10.1002/dmrr.3523
PMCID: PMC9286639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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